Document Detail

Respiratory symptoms/diseases, impaired lung function, and drug use in two Italian general population samples.
MedLine Citation:
PMID:  17905576     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Research and practice indicate that a sizeable amount of prescribed drugs is never used. AIM: To assess the habitual up-take of medicines in subjects with respiratory symptoms/diseases or impaired lung function in general population samples. METHODS: Data regard 4010 subjects (8-88 years) from the rural area of Po River Delta (North Italy) and the urban area of Pisa (North-Central Italy). Analyses concern the habitual use of any or specific medicines (broncho-pulmonary, anti-allergic, cardio-vascular, diuretic) in subjects with asthma, chronic bronchitis/emphysema (COPD), COPD or chronic cough/phlegm (COPDsx), and airways obstruction (AO, FEV(1)/FVC<70%). RESULTS: Asthma, COPD, COPDsx, and AO were present in 6%, 5%, 21%, and 13% of cases, respectively. Only 37% and 21% of subjects with respiratory symptoms/diseases used any or specific medicines, respectively. The subjects with COPD exhibited the highest prevalence of assumption (59% for any drug, 38% for specific medicines), followed by asthmatics (42% and 30%), and subjects with AO (40% and 25%). After accounting for sex, age, residence area, smoking habit, education, and presence of comorbidity, the conditions significantly related to any medicine up-take were COPD (OR 1.65, 95% CI 1.08-2.53) and asthma (OR 1.47, 95% CI 1.01-2.12). Only asthma resulted significantly associated with the use of specific drugs (OR 3.11, 95% CI 1.94-4.97). Drug use was higher in the urban than in the rural area. CONCLUSION: The results indicate that most people in the general population do not use drugs, in spite of reported respiratory disorders. The underuse of medicines seems lower in the urban area.
Marzia Simoni; Laura Carrozzi; Sandra Baldacci; Marco Borbotti; Francesco Pistelli; Francesco Di Pede; Sara Maio; Anna Angino; Giovanni Viegi
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2007-10-01
Journal Detail:
Title:  Respiratory medicine     Volume:  102     ISSN:  0954-6111     ISO Abbreviation:  Respir Med     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2007-11-30     Completed Date:  2008-08-14     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908438     Medline TA:  Respir Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  82-91     Citation Subset:  IM    
Pulmonary Environmental Epidemiology Unit, CNR Institute of Clinical Physiology, Via Trieste, 41, 56126 Pisa, Italy.
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MeSH Terms
Aged, 80 and over
Anti-Allergic Agents / administration & dosage
Asthma / drug therapy*,  epidemiology
Attitude to Health*
Bronchodilator Agents / administration & dosage
Cardiovascular Agents / administration & dosage
Child, Preschool
Diuretics / administration & dosage
Italy / epidemiology
Middle Aged
Pulmonary Disease, Chronic Obstructive / drug therapy*,  epidemiology
Regression Analysis
Respiration Disorders / drug therapy*,  epidemiology
Rural Health / statistics & numerical data
Treatment Refusal / statistics & numerical data
Reg. No./Substance:
0/Anti-Allergic Agents; 0/Bronchodilator Agents; 0/Cardiovascular Agents; 0/Diuretics

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