Document Detail

Respiratory and haemodynamic effects of lateral thoracotomy or sternotomy in mechanically ventilated rats.
MedLine Citation:
PMID:  3918867     Owner:  NLM     Status:  MEDLINE    
We compared left lateral thoracotomy and sternotomy in rats which were mechanically ventilated for at least 1 h in order to perfect the technique and the surveillance of thoracic opening. Lateral thoracotomy proved to be superior to sternotomy as it was associated with a lower mortality within the first 24 h (20% compared with 50%; p less than 0.05). Lateral thoracotomy causes a smaller reduction in mean blood pressure (104 +/- 11 vs. 71 +/- 7 mm Hg; mean +/- SD; p less than 0.05). Furthermore, following lateral thoracotomy, the rats had a higher postoperative PaO2 (77 +/- 16 vs. 72 +/- 7 Torr) and a lower PaCO2 (29.5 +/- 1.5 vs. 35 +/- 4.3 Torr), although these differences were not statistically significant.
J P Duchatelle; P Vivet; M Cortes; O Groussard; J J Pocidalo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes     Volume:  17     ISSN:  0014-312X     ISO Abbreviation:  Eur Surg Res     Publication Date:  1985  
Date Detail:
Created Date:  1985-03-27     Completed Date:  1985-03-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0174752     Medline TA:  Eur Surg Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  10-6     Citation Subset:  IM    
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MeSH Terms
Blood Pressure
Carbon Dioxide / blood
Heart Rate
Lung / pathology
Lung Transplantation*
Models, Cardiovascular
Oxygen / blood
Rats, Inbred Strains
Sternum / surgery
Thoracic Surgery / methods
Reg. No./Substance:
124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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