Document Detail

Respiratory gas exchange by high-efficiency hemodialyzers.
MedLine Citation:
PMID:  673097     Owner:  NLM     Status:  MEDLINE    
The effects of respiratory gas mass-transfer by high-efficiency hemodialyzers with regard to respiratory status and acid-base balance were studied in three groups of patients. Patients dialyzed with acetate dialysate and a single pass delivery system (group I) and those dialyzed with the same dialysate and a recirculating single pass system (group II) had significant intradialytic decreases in PCO2 (p is less than 0.05), while patients hemodialyzed aginst a carbon dioxide/bicarbonate dialysate (group III) had no significant alterations in arterial PCO2. The massfransfer rate of carbon dioxide was 0.3 mM/min in group I and 0.2 mM/min in group II. The hypocapnia caused by dialyzer mass-transfer of carbon dioxide was associated with a significant drop in minute ventilation volume and a decrease in PO2 which was significant in group I (p is less than 0.05). Although bicarbonate mass-transfer reduced serum bicarbonate levels, the loss of carbon dioxide to the dialysate resulted in an increased arterial pH during dialysis.
N Tolchin; J L Roberts; E J Lewis
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Nephron     Volume:  21     ISSN:  0028-2766     ISO Abbreviation:  Nephron     Publication Date:  1978  
Date Detail:
Created Date:  1978-09-25     Completed Date:  1978-09-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0331777     Medline TA:  Nephron     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  137-45     Citation Subset:  IM    
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MeSH Terms
Acid-Base Equilibrium
Blood Gas Analysis
Carbon Dioxide / blood*
Kidney Failure, Chronic / therapy*
Middle Aged
Oxygen / blood
Renal Dialysis / methods*
Reg. No./Substance:
0/Acetates; 0/Bicarbonates; 124-38-9/Carbon Dioxide; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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