Document Detail

Respiratory function monitoring to reduce mortality and morbidity in newborn infants receiving resuscitation.
MedLine Citation:
PMID:  20824878     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: A respiratory function monitor is routinely used in neonatal intensive care units to continuously measure and display airway pressures, tidal volume and leak during ventilation. During positive pressure ventilation in the delivery room, clinical signs are used to monitor the effectiveness of ventilation. The additional use of a respiratory function monitor during positive pressure ventilation in the delivery room might help to improve the effectiveness of ventilation.
OBJECTIVES: To determine whether the use of a respiratory function monitor in addition to clinical assessment compared to clinical assessment alone in newborn infants resuscitated with positive pressure ventilation reduces mortality and morbidity.
SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library, Issue 3, 2010), MEDLINE (January 1996 to March 2010), EMBASE (January 1980 to March 2010) and CINAHL (January 1982 to March 2010). Clinical trials registers and the abstracts of the Society for Pediatric Research and the European Society for Pediatric Research were searched from 2004 to 2009. No language restrictions were applied.
SELECTION CRITERIA: We planned to include randomised and quasi-randomised controlled trials and cluster trials that compared the use of a respiratory function monitor in addition to clinical assessment, compared to clinical assessment alone, in newborn infants resuscitated with positive pressure ventilation.
DATA COLLECTION AND ANALYSIS: Two review authors independently evaluated the search results against the selection criteria. Data extraction and risk of bias assessment were not performed because there were no studies that met our inclusion criteria.
MAIN RESULTS: No studies were found meeting the criteria for inclusion in this review
AUTHORS' CONCLUSIONS: There is insufficient evidence to determine the efficacy and safety of a respiratory function monitor in addition to clinical assessment during positive pressure ventilation at neonatal resuscitation. Randomised clinical trials comparing positive pressure ventilation with and without a respiratory function monitor in addition to clinical assessment at neonatal resuscitation are warranted.
Georg M Schmölzer; Colin J Morley; Peter G Davis
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-09-08
Journal Detail:
Title:  The Cochrane database of systematic reviews     Volume:  -     ISSN:  1469-493X     ISO Abbreviation:  Cochrane Database Syst Rev     Publication Date:  2010  
Date Detail:
Created Date:  2010-09-08     Completed Date:  2010-10-18     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  100909747     Medline TA:  Cochrane Database Syst Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  CD008437     Citation Subset:  IM    
Department of Newborn Research, The Royal Women's Hospital, 20 Flemington Road, Parkville, Victoria, Australia, 3052.
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MeSH Terms
Infant, Newborn
Monitoring, Physiologic / instrumentation*
Positive-Pressure Respiration / instrumentation*,  methods,  mortality
Resuscitation / instrumentation*,  mortality
Ventilators, Mechanical*
Comment In:
Int J Evid Based Healthc. 2011 Mar;9(1):73   [PMID:  21332667 ]

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