Document Detail

Respiratory function following premedication with droperidol or diazepam.
MedLine Citation:
PMID:  569994     Owner:  NLM     Status:  MEDLINE    
Respiratory function was measured before and 1 hour after premedication with diazepam (10 mg IM) or droperidol (5 mg IM) in 2 groups of 14 normal patients scheduled for elective surgery. Diazepam had no significant effects on respiratory rate, tidal volume, minute ventilation, dead space, VD/VT %, alveolar ventilation, expired Po2, or Pco2, end-tidal Pco2, arterial Po2 or Pco2, or alveolar-arterial Po2 or Pco2 gradients. Droperidol was associated with statistically significant but modest reductions in tidal volume (-13.3%) and minute ventilation (-8.4%) while other respiratory functions remained unaffected.
D Soroker; E Barzilay; S Konichezky; I Bruderman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Anesthesia and analgesia     Volume:  57     ISSN:  0003-2999     ISO Abbreviation:  Anesth. Analg.     Publication Date:    1978 Nov-Dec
Date Detail:
Created Date:  1979-03-28     Completed Date:  1979-03-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1310650     Medline TA:  Anesth Analg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  695-9     Citation Subset:  AIM; IM    
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MeSH Terms
Depression, Chemical
Diazepam / administration & dosage,  adverse effects*
Droperidol / administration & dosage,  adverse effects*
Drug Evaluation
Injections, Intramuscular
Middle Aged
Preanesthetic Medication / adverse effects*,  methods
Respiration / drug effects*
Respiratory Function Tests
Time Factors
Reg. No./Substance:
439-14-5/Diazepam; 548-73-2/Droperidol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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