| Respiratory failure in the neurological patient: the diagnosis of neurogenic pulmonary edema. | |
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MedLine Citation:
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PMID: 11497073 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Neurogenic pulmonary edema (NPE) is a potential complication of a central nervous system (CNS) insult such as intracranial hemorrhage, uncontrolled generalized seizures, head trauma, tumors, and neurosurgical procedures. The proposed etiology is massive sympathetic discharge following a CNS event. The pathogenesis is not completely understood. However, there are two theories on how NPE occurs: the blast theory and the permeability defect theory. There is evidence for both theories, and NPE is probably the result of a combination of the two. The treatment is mainly supportive with the use of mechanical ventilation and alpha-adrenergic blocking agents while managing increased intracranial pressure. A thorough understanding of the pathophysiological mechanisms behind the development of NPE aids in the management of these patients to prevent further complications. |
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Authors:
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A M Pyeron |
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Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses Volume: 33 ISSN: 0888-0395 ISO Abbreviation: J Neurosci Nurs Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-08-10 Completed Date: 2001-12-07 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 8603596 Medline TA: J Neurosci Nurs Country: United States |
Other Details:
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Languages: eng Pagination: 203-7 Citation Subset: IM; N |
Affiliation:
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Merck & Co, Inc. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Antagonists
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therapeutic use Central Nervous System Diseases / complications*, physiopathology, therapy Cerebral Hemorrhage / complications*, physiopathology, therapy Combined Modality Therapy Female Humans Middle Aged Nursing Assessment Patient Care Planning Postoperative Care Pulmonary Edema / diagnosis, etiology*, physiopathology, therapy Respiration, Artificial Respiratory Insufficiency / diagnosis, etiology*, physiopathology, therapy |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Antagonists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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