| Respiratory, cerebrovascular and cardiovascular responses to isocapnic hypoxia. | |
| | |
MedLine Citation:
|
PMID: 21939786 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
We simultaneously measured respiratory, cerebrovascular and cardiovascular responses to 10-min of isoxic hypoxia at three constant CO(2) tensions in 15 subjects. We observed four response patterns, some novel, for ventilation, middle cerebral artery blood flow velocity, heart rate and mean arterial blood pressure. The occurrence of the response patterns was correlated between some measures. Isoxic hyperoxic and hypoxic ventilatory sensitivities to CO(2) derived from these responses were equivalent to those measured with modified (Duffin) rebreathing tests, but cerebrovascular sensitivities were not. We suggest the different ventilatory response patterns reflect the time course of carotid body afferent activity; in some individuals, carotid body function changes during hypoxia in more complex ways than previously thought. We concluded that isoxic hyperoxic and hypoxic ventilatory sensitivities to CO(2) can be measured using multiple hypoxic ventilatory response tests only if care is taken choosing the isocapnic CO(2) levels used, but a similar approach to measuring the cerebrovascular response to isocapnic hyperoxia and hypoxia is unfeasible. |
| | |
Authors:
|
A Battisti-Charbonney; J A Fisher; J Duffin |
Related Documents
:
|
6429666 - Role of the blood bank in bone marrow transplantation. 11485086 - A preliminary study of the distribution of blood group systems in thai blood donors det... 15749736 - Transfusion for a patient of cis-ab blood type undergoing a redo cardiac operation. 11942116 - Frequencies of feline blood types in hungary. 3667426 - Testicular hemodynamic changes after the surgical creation of a varicocele in the rat. ... 22267036 - Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-14 |
Journal Detail:
|
Title: Respiratory physiology & neurobiology Volume: - ISSN: 1878-1519 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101140022 Medline TA: Respir Physiol Neurobiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 Elsevier B.V. All rights reserved. |
Affiliation:
|
Department of Physiology, University of Toronto, Toronto, ON, Canada M5S 1A8. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Extra-articular manifestations of rheumatoid arthritis: An update.
Next Document: Coupling of dyspnea perception and tachypneic breathing during hypercapnia.