| Respiratory Syncytial Virus Prophylaxis in Special Populations: Is it Something Worth Considering in Cystic Fibrosis and Immunosuppression? | |
| | |
MedLine Citation:
|
PMID: 22477829 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Respiratory syncytial virus (RSV) bronchiolitis is the leading cause of infant hospitalization in the United States. Prophylaxis with palivizumab is effective in reducing RSV hospitalizations in premature infants and in infants or children with chronic lung disease or congenital heart disease. Patients with CF or those who are immunocompromised may be at increased risk for RSV infection-related complications; hence, prophylaxis may prove beneficial to these populations. The extent of palivizumab use in the CF and immunocompromised populations is variable. Palivizumab appears to be safe and may be effective in infants and young children with CF and immunocompromise. However, well-designed, randomized, controlled trials published in peer-reviewed journals are lacking, and its routine use can therefore not be recommended at this time. If used in patients with CF or those who are immunocompromised, RSV prophylaxis should be restricted to peak outbreak months in order to optimize the cost benefit of palivizumab. |
| | |
Authors:
|
William A Prescott; David J Hutchinson |
Related Documents
:
|
22925509 - Infant pointing serves an interrogative function. 1118439 - Resuscitation of the newborn. 18492509 - Accuracy of pulse oximetry measurement of heart rate of newborn infants in the delivery... 9386659 - Rapid estimation of insertional length of endotracheal intubation in newborn infants. 15625399 - Maxillary palp glomeruli and ipsilateral projections in the antennal lobe of drosophila... 18929159 - Consequences of neonatal resuscitation with supplemental oxygen. 6977459 - Predominance of macrophage-colony formation in human cord blood. 3841469 - Infant pulmonary vascular model based on the pulmonary input impedance spectrum. 19815939 - Pain in neonates during screening for retinopathy of prematurity using binocular indire... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG Volume: 16 ISSN: 1551-6776 ISO Abbreviation: J Pediatr Pharmacol Ther Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2012-04-05 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101089851 Medline TA: J Pediatr Pharmacol Ther Country: United States |
Other Details:
|
Languages: eng Pagination: 77-86 Citation Subset: - |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Carbamazepine-induced acute generalized exanthematous pustulosis: a case report.
Next Document: Hyperphosphatemia in pediatric oncology patients receiving liposomal amphotericin B.