| Respiratory syncytial virus infection and palivizumab: are families receiving accurate information? | |
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MedLine Citation:
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PMID: 19784911 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to assess the accuracy of information provided by medical practitioners to families regarding the efficacy and limitations of prophylaxis with palivizumab for respiratory syncytial virus (RSV) infection in infants. A single-question survey was distributed to medical practitioners who described themselves as having both prescribed palivizumab for infants and discussed the effects of the drug with families. Responses were anonymous and returned immediately after reviewing the survey question. Respondents were requested to choose the answer that most closely resembled their understanding of palivizumab effects on the degree of illness and severity of RSV infection. All surveys distributed were completed and answers assessed by medical specialty. A total of 456 surveys were returned. Neonatologists and pediatricians accounted for the majority of responses. The answer that most closely reflects the medical literature, that palivizumab will decrease hospitalization but have no effect on need for mechanical intubation or mortality, was chosen only 2% of the time. Families are not receiving accurate information regarding the expected potential benefits and limitations of immunoprophylaxis with palivizumab. This is a very expensive drug with unclear cost-effectiveness. If changes are to be made to current recommendations as to use of palivizumab, families must receive informed consent that accurately reflects the literature. |
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Authors:
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Joel H Weiner |
Publication Detail:
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Type: Journal Article Date: 2009-09-26 |
Journal Detail:
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Title: American journal of perinatology Volume: 27 ISSN: 1098-8785 ISO Abbreviation: Am J Perinatol Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-22 Completed Date: 2010-05-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 219-23 Citation Subset: IM |
Copyright Information:
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Thieme Medical Publishers. |
Affiliation:
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Department of Neonatology, University of Massachusetts Memorial Hospital, Worcester, Massachusetts 01605, USA. jtteupton@aol.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Monoclonal / economics, therapeutic use* Antiviral Agents / economics, therapeutic use* Attitude of Health Personnel* Cost-Benefit Analysis Female Health Knowledge, Attitudes, Practice Humans Infant, Newborn Length of Stay / statistics & numerical data Male Middle Aged Patient Education as Topic / statistics & numerical data* Professional-Family Relations* Respiratory Syncytial Virus Infections / drug therapy*, economics United States / epidemiology Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal; 0/Antiviral Agents; 0/palivizumab |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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