Document Detail


Respiration rate, heart rate, and body temperature values in cynomolgus monkeys (Macaca fascicularis) during barbiturate anesthesia.
MedLine Citation:
PMID:  3795256     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Respiration rate, heart rate, and body temperature values were obtained from 14 cynomolgus monkeys (Macaca fascicularis) during neurosurgery under barbiturate anesthesia. Vital sign values markedly declined below baseline during the early stages of surgery, steadily increased as surgery progressed and neared completion, and finally returned to baseline by the end of the postsurgical recovery period. There was considerable variability among the 14 monkeys, but the ranking of each monkey relative to the others remained constant across the period of observation. The findings suggested that the cynomolgus monkey may be more sensitive to barbiturates than the rhesus monkey, and cynomolgus monkeys may exhibit considerable individual differences in their sensitivity to barbiturates.
Authors:
S Zola-Morgan; C Micheletti
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of medical primatology     Volume:  15     ISSN:  0047-2565     ISO Abbreviation:  J. Med. Primatol.     Publication Date:  1986  
Date Detail:
Created Date:  1987-02-10     Completed Date:  1987-02-10     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0320626     Medline TA:  J Med Primatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  399-408     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Anesthesia, General / veterinary
Animals
Body Temperature*
Female
Heart Rate*
Macaca / surgery*
Macaca fascicularis / physiology,  surgery*
Male
Microcomputers
Neurosurgical Procedures
Pentobarbital*
Respiration*
Grant Support
ID/Acronym/Agency:
NS 19063/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
76-74-4/Pentobarbital

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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