Document Detail

Respiration of mitochondria from the gonads of the sea urchin, Strongylocentrotus droebachiensis: the effects of petroleum fractions on oxygen consumption.
MedLine Citation:
PMID:  2858338     Owner:  NLM     Status:  MEDLINE    
The respiration of mitochondria from gonads of Strongylocentrotus droebachiensis has been studied in the presence of 2-oxoglutarate, glutamate and succinate. The rate of oxygen consumption increased with temperature between 4 and 20 degrees C. Removal of gametes from ripe gonads was necessary to obtain good respiring mitochondria. Equilibration of respiration media with various petroleum fractions reduced the rate of oxygen consumption and the coupling of O2 consumption to ADP utilization. Lighter fractions (leaded gasolines, unleaded gasoline and related fractions) were more deleterious than medium fractions (kerosene and fuel oil). Heavy fraction (bunker C, vacuum bottoms and crude oil) were least deleterious. Tetraethyl lead contributed to the toxicity of the leaded fractions.
P J Davis; J Bragg; K M Keough
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology     Volume:  80     ISSN:  0742-8413     ISO Abbreviation:  Comp. Biochem. Physiol. C, Comp. Pharmacol. Toxicol.     Publication Date:  1985  
Date Detail:
Created Date:  1985-05-17     Completed Date:  1985-05-17     Revised Date:  2007-07-23    
Medline Journal Info:
Nlm Unique ID:  8310013     Medline TA:  Comp Biochem Physiol C     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  155-60     Citation Subset:  IM    
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MeSH Terms
Adenosine Diphosphate / metabolism
Gonads / drug effects,  metabolism,  ultrastructure
Hydrocarbons / pharmacology
Mitochondria / drug effects,  metabolism*
Oxygen Consumption / drug effects*
Petroleum / toxicity*
Sea Urchins / metabolism*
Reg. No./Substance:
0/Hydrocarbons; 0/Petroleum; 58-64-0/Adenosine Diphosphate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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