Document Detail

Resorption kinetics of osseous substitute: natural coral and synthetic hydroxyapatite.
MedLine Citation:
PMID:  8805984     Owner:  NLM     Status:  MEDLINE    
Coral and hydroxyapatite may be used as substitution biomaterials for bone grafts. In this work, we extracted the implants from the femora to study the kinetics of elementary mineral transformation of the osseous substitutes. The use of physical analysis methods such as PIXE (particle-induced X-ray emission) shows that coral and hydroxyapatite, after their implantation in vivo, reach a mineral composition comparable with that of bone. For the first time we have measured the concentration of mineral elements, at different time intervals after implantation, along a cross-section. The distribution according to mineral elements (Ca, P, Sr, Zn, Fe) in the implant, in the receiver site and also at the interface, showed that the kinetics of coral resorption was faster than that of hydroxyapatite; in the same way, the osseous attack was not global but, rather, centripetal.
F Braye; J L Irigaray; E Jallot; H Oudadesse; G Weber; N Deschamps; C Deschamps; P Frayssinet; P Tourenne; H Tixier; S Terver; J Lefaivre; A Amirabadi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biomaterials     Volume:  17     ISSN:  0142-9612     ISO Abbreviation:  Biomaterials     Publication Date:  1996 Jul 
Date Detail:
Created Date:  1996-12-13     Completed Date:  1996-12-13     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8100316     Medline TA:  Biomaterials     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1345-50     Citation Subset:  IM    
Laboratoire de Physique Corpusculaire de Clermont-Ferrand, IN2P3/C.N.R.S. et Université Blaise Pascal, Aubiere, France.
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MeSH Terms
Bone Resorption / metabolism*
Bone Substitutes / pharmacokinetics*
Durapatite / pharmacokinetics*
Materials Testing / instrumentation,  methods
Prostheses and Implants
Spectrometry, X-Ray Emission
Time Factors
Reg. No./Substance:
0/Bone Substitutes; 1306-06-5/Durapatite

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