Document Detail


Resorbable polyesters: composition, properties, applications.
MedLine Citation:
PMID:  10171204     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Synthetic polymers, in particular polyesters based on lactic acid, glycolic acid and other raw materials are described for medical and technical applications. Their main advantages are compatibility and safety. As they are degradable in the human body they are particularly suitable for implants needed only temporarily for the healing process. Resorbable polyesters are produced by direct polycondensation or ring opening polymerization resulting in a broad range of polymers with different features. The main properties such as degradation (hydrolytic and thermal), crystallinity and mechanical strengths are discussed. These polyesters, which can be processed like other thermo-plastic polymers by extrusion and injection moulding, are used mainly for wound closure products (sutures, staples, clips), fracture fixation devices (nails, screws, plates) and parenteral depot systems for the sustained release of drugs. Possibilities for polymer and process improvement to develop better implants and additional applications are presented.
Authors:
B Amecke; D Bendix; G Entenmann
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Clinical materials     Volume:  10     ISSN:  0267-6605     ISO Abbreviation:  Clin Mater     Publication Date:  1992  
Date Detail:
Created Date:  1992-10-29     Completed Date:  1992-10-29     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8707278     Medline TA:  Clin Mater     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  47-50     Citation Subset:  T    
Affiliation:
Chemicals Division, Boehringer Ingelheim KG, Germany.
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MeSH Terms
Descriptor/Qualifier:
Biocompatible Materials* / chemistry
Biodegradation, Environmental
Equipment Design
Forecasting
Humans
Polyesters / chemistry*
Prostheses and Implants* / trends
Chemical
Reg. No./Substance:
0/Biocompatible Materials; 0/Polyesters

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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