Document Detail


Resolving DNA at efficiencies of more than a million plates per meter using bare narrow open capillaries without sieving matrices.
MedLine Citation:
PMID:  23459665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a novel approach for effectively separating DNA molecules in free solution. The method uses a bare narrow open capillary without any sieving matrices to resolve a wide size-range of DNA fragments at efficiencies of more than a million plates per meter routinely.
Authors:
Zaifang Zhu; Lei Liu; Wei Wang; Joann J Lu; Xiayan Wang; Shaorong Liu
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  49     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-03-13     Completed Date:  2013-09-10     Revised Date:  2014-04-14    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  2897-9     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Chromatography / methods*
DNA / chemistry*,  isolation & purification*
Hydrodynamics*
Solutions
Grant Support
ID/Acronym/Agency:
R21 GM104526/GM/NIGMS NIH HHS; R21GM104526/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Solutions; 9007-49-2/DNA
Comments/Corrections

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