Document Detail

Resolution of spur cell anemia with liver transplantation: a case report and review of the literature.
MedLine Citation:
PMID:  9565106     Owner:  NLM     Status:  MEDLINE    
Spur cell anemia is an acquired hemolytic anemia, characterized by an increased percentage of abnormally shaped erythrocytes that are known as acanthocytes. The erythrocytes have numerous spicules irregularly distributed over the cell surface. Spur cell anemia has been described to occur in several conditions, including cirrhosis. We present an unusual case of a young patient with hemochromatosis, alcohol abuse, decompensated cirrhosis, and spur cell anemia who had a spontaneous resolution of the spur cell anemia after orthotopic liver transplantation. This finding suggests that the diseased liver may contribute to transformation of the erythrocyte to the spur cell.
A A Chitale; R K Sterling; A B Post; B J Silver; D C Mulligan; J A Schulak
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Transplantation     Volume:  65     ISSN:  0041-1337     ISO Abbreviation:  Transplantation     Publication Date:  1998 Apr 
Date Detail:
Created Date:  1998-05-08     Completed Date:  1998-05-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0132144     Medline TA:  Transplantation     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  993-5     Citation Subset:  IM    
Department of Medicine, University Hospitals of Cleveland, Case Western Reserve University, Ohio, USA.
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MeSH Terms
Anemia, Hemolytic / blood,  complications,  therapy*
Hemochromatosis / blood,  chemically induced
Liver Diseases / blood,  complications
Liver Transplantation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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