Document Detail


Resolution of alkenylacylglycerol moieties of natural glycerophospholipids by gas-liquid chromatography on polar capillary columns.
MedLine Citation:
PMID:  6467078     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A sensitive and practical procedure has been developed for the determination of the sn-1-alk-1-enyl-2-acylglycerol moieties of natural glycerophospholipids using capillary gas-liquid chromatography with flame ionization detection. The method gives excellent resolution and quantitative estimates for molecular species according to carbon number and degree of unsaturation. The diradylglycerols are released from the glycerophospholipids by hydrolysis with phospholipase C and the alk-1-enylacylglycerols are resolved by thin-layer chromatography. Either the trimethylsilyl or the tertiary-butyldimethylsilyl ethers are then resolved at 250 degrees C by gas-liquid chromatography on a glass capillary column wall-coated with a polar cyanopropylsiloxane polymer using hydrogen as the carrier gas. The method has been applied to the analysis of the alk-1-enylacyl- and diacyl-glycerol moieties of the phosphatidylethanolamines of rat heart and kidney.
Authors:
J J Myher; A Kuksis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire     Volume:  62     ISSN:  0714-7511     ISO Abbreviation:  Can. J. Biochem. Cell Biol.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-10-11     Completed Date:  1984-10-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8302763     Medline TA:  Can J Biochem Cell Biol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  352-62     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Chromatography, Gas / methods
Fatty Acids, Unsaturated / analysis*
Gas Chromatography-Mass Spectrometry / methods
Glycerides / analysis*
Kidney / analysis
Myocardium / analysis
Phosphatidic Acids / analysis*
Phosphatidylethanolamines / analysis
Phospholipids / analysis*
Rats
Type C Phospholipases / diagnostic use
Grant Support
ID/Acronym/Agency:
NIH-NHLI-72-917/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Fatty Acids, Unsaturated; 0/Glycerides; 0/Phosphatidic Acids; 0/Phosphatidylethanolamines; 0/Phospholipids; EC 3.1.4.-/Type C Phospholipases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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