Document Detail

Resolution of Lyme arthritis, acute or prolonged: a new look.
MedLine Citation:
PMID:  11128048     Owner:  NLM     Status:  MEDLINE    
I have presented a paradigm for the pathogenesis and resolution of Lyme arthritis founded upon the clinical facts that describe its natural history, and centered about a process of intermittent immune recognition of what may sometimes be an array of antigenic variants. The model applies both to acute and to prolonged (chronic) disease. If it proves to be correct, it represents a variation of the struggle between parasite and host that is probably not limited to Lyme disease.
S E Malawista
Related Documents :
12148968 - Lyme disease in childhood: report of one case.
17961858 - Rocky mountain spotted fever.
2405018 - Comparison of indirect immunofluorescent-antibody assay, enzyme-linked immunosorbent as...
14680128 - Geographic information systems and spatial analysis of adult ixodes scapularis (acari: ...
18979948 - Pathways linking late-life depression to persistent cognitive impairment and dementia.
24648338 - The a4 study: stopping ad before symptoms begin?
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Inflammation     Volume:  24     ISSN:  0360-3997     ISO Abbreviation:  Inflammation     Publication Date:  2000 Dec 
Date Detail:
Created Date:  2000-12-20     Completed Date:  2001-02-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7600105     Medline TA:  Inflammation     Country:  United States    
Other Details:
Languages:  eng     Pagination:  493-504     Citation Subset:  IM    
Department of Internal Medicine, Yale University School at Medicine, New Haven, Connecticut, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Acute Disease
Antigens / genetics
Chronic Disease
Genetic Variation
Lyme Disease / immunology,  physiopathology*,  therapy
Grant Support
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Non-competitive inhibition of kainate-induced currents by diethylstilbestrol in acutely isolated mou...
Next Document:  Regulation of chemokine mRNA expression in a rat model of vanadium-induced pulmonary inflammation.