Document Detail

Resistant oral mucosal lesions in pemphigus vulgaris responsive to double filtration plasmapheresis: First case report from Turkey.
MedLine Citation:
PMID:  23415411     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Adjuvant therapeutic methods are employed when pemphigus vulgaris (PV) fails to be controlled by conventional corticosteroid treatment.
OBJECTIVE: The efficacy of double filtration plasmapheresis (DFPP) was investigated in a PV patient with severe, refractory mucosal disease.
METHODS: A total of 3 DFPP cycles, each cycle consisting of 5 double filtration sessions conducted on alternate days was completed.
RESULTS: DFPP provided immediate clinical relief of symptoms as well as a significant decrease in anti-desmoglein antibody levels and allowed for a much lower corticosteroid dose.
CONCLUSION: DFPP was an effective and safe adjuvant therapy in our patient with PV and it offers a valid treatment option in PV patients with recalcitrant disease.
E Savk; M Uslu; I Yavaşoğlu; G Kadıköylü; N Sendur; G Karaman
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2013-02-13
Journal Detail:
Title:  Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis     Volume:  48     ISSN:  1473-0502     ISO Abbreviation:  Transfus. Apher. Sci.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-05-07     Completed Date:  2013-12-09     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  101095653     Medline TA:  Transfus Apher Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  273-5     Citation Subset:  T    
Copyright Information:
Copyright © 2013 Elsevier Ltd. All rights reserved.
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MeSH Terms
Adrenal Cortex Hormones / administration & dosage
Autoantibodies* / blood,  immunology
Desmin / immunology*
Middle Aged
Mouth Diseases* / blood,  immunology,  pathology,  therapy
Mouth Mucosa* / immunology,  metabolism,  pathology
Pemphigus* / blood,  immunology,  pathology,  therapy
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Autoantibodies; 0/Desmin

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