Document Detail


Resistant hypertension: a methodological approach to diagnosis and treatment.
MedLine Citation:
PMID:  17679742     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Resistant hypertension affects approximately 10% of the hypertensive patient population. It should be differentiated from white-coat hypertension and pseudo-resistant hypertension. Non-compliance to anti-hypertensive therapy remains the most common cause of resistant hypertension. Primary hyperaldosteronism is not as uncommon as previously thought, but its prevalence depends on the selected population. Low-renin resistant hypertension responds to aldosterone blockade when other drugs are apparently inadequately effective. Sleep apnea syndrome can also contribute to the development of resistant hypertension by stimulating aldosterone secretion, which leads to vascular damage and may promote scarring through more direct actions. Normal blood levels of potassium in resistant hypertension do not exclude the possible presence of hyperaldosteronism.
Authors:
Nihad A M Tamimi
Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia     Volume:  18     ISSN:  1319-2442     ISO Abbreviation:  Saudi J Kidney Dis Transpl     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-07     Completed Date:  2008-01-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9436968     Medline TA:  Saudi J Kidney Dis Transpl     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  337-45     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aldosterone / physiology
Diagnosis, Differential
Drug Resistance
Humans
Hyperaldosteronism / complications
Hypertension / diagnosis*,  drug therapy,  etiology
Patient Compliance
Sleep Apnea Syndromes / complications
Chemical
Reg. No./Substance:
52-39-1/Aldosterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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