Document Detail

Resistance training improves strength and functional measures in patients with end-stage renal disease.
MedLine Citation:
PMID:  12148109     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The current study was designed to examine the effect of 12 weeks of resistance training on strength and functional ability in 10 medically stable hemodialysis patients (age, 42.8 +/- 4.4 years). METHODS: Subjects were tested on four separate occasions, each separated by 6 weeks. The first (T1) and second tests (T2) were controls with no exercise intervention between them. T3 followed 6 weeks of resistance training, and T4 occurred after 12 weeks of training. Variables tested included percentage of body fat, distance covered in the 6-minute walk test, peak torque of quadriceps muscles of the dominant leg, maximal handgrip strength, normal and maximal walking speeds, and time to complete 10 repetitions of the sit-to-stand-to-sit test. Data were analyzed by means of a one-way repeated-measures analysis of variance procedure. RESULTS: Results indicate that after 12 weeks of training, there was a significant (P < 0.05) increase (12.7%) in peak torque at 90 degrees /s (139.1 +/- 19.3 nm) compared with T1 and T2 (mean, 124.1 +/- 18.7 [SEM]; 123.5 +/- 16.9 Nm), respectively. The distance covered during the 6-minute walk was increased ( approximately 5%; P < 0.05) compared with baseline (T1, 522.1 +/- 46.2 m; 521.9 +/- 48.5 m) after 6 weeks of training (548.3 +/- 52.1 m) and remained elevated at week 12 (546.5 +/- 54.2 m). Maximal walking speed was increased (P < 0.05) by week 12 (195.9 +/- 15.4 cm/s) compared with baseline (T1, 182.9 +/- 12.7; 185.5 +/- 13.0 cm/s). Time to complete 10 repetitions of the sit-to-stand-to-sit test decreased at 12 weeks (17.8 +/- 1.9 seconds) versus baseline (T1, 20.3 +/- 1.5 seconds; T2, 20.6 +/- 5.5 seconds). CONCLUSION: Resistance training can be used safely to increase strength and functional capacity in stable hemodialysis patients.
Samuel Headley; Michael Germain; Patrick Mailloux; Jeffrey Mulhern; Brian Ashworth; Jami Burris; Britton Brewer; Bradley C Nindl; Bradley Nindl; MaryAnn Coughlin; Robert Welles; Margaret Jones
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Publication Detail:
Type:  Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  40     ISSN:  1523-6838     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  2002 Aug 
Date Detail:
Created Date:  2002-07-30     Completed Date:  2002-08-12     Revised Date:  2008-11-25    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  355-64     Citation Subset:  IM    
Copyright Information:
Copyright 2002 by the National Kidney Foundation, Inc.
Springfield College, Pioneer Valley Dialysis Center, Military Performance Division, US Army Research, Springfield, MA 01109, USA.
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MeSH Terms
Body Composition / physiology
Exercise Therapy / methods*
Gait / physiology
Hand Strength / physiology
Kidney Failure, Chronic / rehabilitation*,  therapy
Middle Aged
Muscle, Skeletal / physiology
Physical Fitness / physiology
Renal Dialysis / methods
Walking / physiology
Weight Lifting / physiology*
Erratum In:
Am J Kidney Dis. 2008 Dec;52(6):1204.
Note: Nindl, Bradley [corrected to Nindl, Bradley C]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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