Document Detail

Resistance training improves muscle function and body composition in patients with hyperthyroidism.
MedLine Citation:
PMID:  16876559     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the effect of resistance training on skeletal muscle performance and body composition in patients with medically treated hyperthyroidism. DESIGN: Nonrandomized controlled trial. SETTING: Large public tertiary hospital. PARTICIPANTS: Sixteen sedentary patients with recent clinical diagnosis and laboratory confirmation of hyperthyroidism (7 men, 9 women; age, 38+/-11 y; weight, 58.4+/-2.6 kg; height, 1.6+/-0.3m) were assigned to the control group (medical therapy; n=9) or training group (medical therapy associated with resistance training; n=7). An age- and sex-matched healthy group served as controls (3 men, 5 women; age, 40+/-3 y; weight, 68.4+/-4.3 kg; height, 1.6+/-0.3m). INTERVENTION: Resistance training twice a week for 16 weeks. MAIN OUTCOME MEASURES: Peak muscular strength (by dynamometry and 1 repetition maximum method) and endurance (30% of peak force) for 7 movements and anthropometric measurements. RESULTS: The hyperthyroid patients as a group had lower baseline overall strength values when compared with healthy subjects (200.3+/-16.0 kg vs 274.9+/-21.8 kg, respectively; P=.006). Overall absolute increases in strength (49 kg vs 91 kg, P<.05) and endurance (78.5x10(2)kg/s vs 176.9x10(2)kg/s, P<.05) were higher in the training group compared with the control group. Body weight increased in both groups, but the sum of muscular circumference increased only in the training group (training group, 92.6+/-3.3 cm vs 97.1+/-3.8 cm; control group, 94.6+/-2.2 cm vs 94.4+/-2.1cm; P<.05), with no change in the sum of skinfolds. CONCLUSIONS: Resistance training accelerates the recovery of skeletal muscle function and promotes weight gain based on muscle mass improvement in patients with medically treated hyperthyroidism.
Kelb Bousquet-Santos; Mario Vaisman; Ney D Barreto; Rubens A Cruz-Filho; Bruno A Salvador; Walter R Frontera; Antonio C Nobrega
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of physical medicine and rehabilitation     Volume:  87     ISSN:  0003-9993     ISO Abbreviation:  Arch Phys Med Rehabil     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-07-31     Completed Date:  2006-09-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985158R     Medline TA:  Arch Phys Med Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1123-30     Citation Subset:  AIM; IM    
Department of Physiology and Pharmacology, Universidade Federal Fluminense, Niteroi, RJ, Brazil.
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MeSH Terms
Body Composition
Hyperthyroidism / physiopathology,  rehabilitation*
Linear Models
Muscle, Skeletal / physiology
Physical Education and Training*
Physical Endurance
Statistics, Nonparametric

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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