Document Detail

Resistance training and bone mineral density during growth.
MedLine Citation:
PMID:  17879877     Owner:  NLM     Status:  MEDLINE    
This study examined the efficacy of two different resistance training programs in enhancing bone modeling and bone mineral density (BMD) in maturating rats. One exercise mode involved lifting a lighter weight with more repetitions (LI), while the other regimen involved lifting a heavier weight with fewer repetitions (HI) where the total volume of work between exercise programs was equivalent by design. Twenty-three male rats were randomly divided into control (Con, n = 8), LI (n = 7), and HI (n = 8) groups. The LI and HI groups were conditioned to climb a vertical ladder with weights appended to their tail 4 days/wk for 6 wks. After training, serum osteocalcin (OC) was significantly (p < 0.05) higher in both HI (45.2 +/- 1.7 ng/ml) and LI (39.1 +/- 2.2 ng/ml) when compared to Con (29.9 +/- 0.9 ng/ml). Left tibial BMD was significantly (p < 0.05) greater for HI (0.231 +/- 0.004 g/cm (2)) when compared to both LI (0.213 +/- 0.003 g/cm (2)) and Con (0.206 +/- 0.005 g/cm (2)) with no significant difference between LI and Con. The results indicate that both HI and LI are effective in elevating serum OC, implicating an osteogenic response; however, only HI resulted in a significant elevation in BMD.
M Z Smith; B M Goettsch; R D Van Ramshorst; J A O'Brien; S V Jaque; K D Sumida
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Publication Detail:
Type:  Journal Article     Date:  2007-09-18
Journal Detail:
Title:  International journal of sports medicine     Volume:  29     ISSN:  0172-4622     ISO Abbreviation:  Int J Sports Med     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-03-25     Completed Date:  2008-09-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8008349     Medline TA:  Int J Sports Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  316-21     Citation Subset:  IM    
Department of Biological Sciences, Chapman University, Orange, CA 92866, USA.
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MeSH Terms
Body Weight / physiology
Bone Density / physiology*
Models, Animal
Muscle Proteins / analysis
Osteocalcin / blood
Physical Conditioning, Animal*
Random Allocation
Rats / growth & development*
Rats, Wistar
Weight Lifting / physiology*
Reg. No./Substance:
0/Muscle Proteins; 104982-03-8/Osteocalcin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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