Document Detail


Resistance to antimicrobial agents and prevalence of R plasmids in Pasteurella multocida from swine.
MedLine Citation:
PMID:  1767987     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Twenty-nine field isolates of porcine Pasteurella multocida were characterized for their capsular and somatic types and were evaluated for their susceptibility to 10 antimicrobial agents. Plasmid DNA-screening experiments were conducted to determine whether a relationship existed between the presence of plasmids and antibiotic resistance. Field isolates of P multocida were susceptible to most of the antimicrobials tested, but all isolates were resistant to clindamycin. Eleven isolates of serogroup D were resistant to 1 or 2 antimicrobial agents. Resistance to sulfonamides and streptomycin was observed in 7 isolates. These isolates contained R plasmids conferring resistance to streptomycin and sulfonamides. The R plasmids belonged to 2 groups, one of 5.6 kilobase and the other of 5.9 kilobase. Restriction endonuclease mapping and DNA hybridization revealed that these R plasmids were related to RSF1010 from Salmonella panama, which also confers resistance to streptomycin and sulfonamides.
Authors:
S Coté; J Harel; R Higgins; M Jacques
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of veterinary research     Volume:  52     ISSN:  0002-9645     ISO Abbreviation:  Am. J. Vet. Res.     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-02-14     Completed Date:  1992-02-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375011     Medline TA:  Am J Vet Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1653-7     Citation Subset:  IM    
Affiliation:
Department of Pathology and Microbiology, Faculty of Veterinary Medicine, University of Montreal.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Bacterial Agents / pharmacology*
DNA Probes
DNA, Bacterial / analysis
Drug Resistance, Microbial / genetics
Nucleic Acid Hybridization
Pasteurella Infections / microbiology,  veterinary
Pasteurella multocida / drug effects*,  genetics
R Factors*
Rhinitis, Atrophic / microbiology,  veterinary*
Swine
Swine Diseases / microbiology*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/DNA Probes; 0/DNA, Bacterial

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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