Document Detail


Resistance of native and circulating modified low-density lipoproteins in human blood to association.
MedLine Citation:
PMID:  15665950     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The resistance of native and circulating modified low-density lipoproteins from human blood to spontaneous and polyethylene glycol-induced association was studied by recording light transmission fluctuations. Circulating modified low-density lipoproteins were less resistant to association than native low-density lipoproteins. Polyethylene glycol-induced association of low-density lipoproteins was irreversible. Our results suggest that atherogenic activity of circulating modified low-density lipoproteins is associated with their increased predisposition to irreversible association.
Authors:
I V Suprun; A A Mel'nichenko; I A Sobenin; O M Panasenko; A N Orekhov
Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  138     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2005-01-24     Completed Date:  2005-07-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  380-3     Citation Subset:  IM    
Affiliation:
Laboratory for Mechanisms of Atherogenesis, Institute of Experimental Cardiology, Russian Cardiology Research-and-Production Complex, Russian Ministry of Health. inat@cardio.ru
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MeSH Terms
Descriptor/Qualifier:
Arteriosclerosis / blood
Chemistry, Physical
Humans
Light
Lipoproteins, LDL / blood*,  chemistry*,  drug effects
Physicochemical Phenomena
Polyethylene Glycols / pharmacology
Chemical
Reg. No./Substance:
0/Lipoproteins, LDL; 0/Polyethylene Glycols

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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