Document Detail


Resistance of cold-exposed rats to aflatoxin.
MedLine Citation:
PMID:  971755     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Male rats kept at a temperature of 4 degrees-5 degrees C were refractory to a lethal dose of aflatoxin compared to animals at 20 degrees-21 degrees C which exhibited a high mortality and marked liver damage. It is suggested that this decreased susceptibility is mediated through a stimulated microsomal drug-metabolizing system in cold environment.
Authors:
T B Tilak; V Nagarajan; P G Tulpule
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experientia     Volume:  32     ISSN:  0014-4754     ISO Abbreviation:  Experientia     Publication Date:  1976 Sep 
Date Detail:
Created Date:  1976-12-03     Completed Date:  1976-12-03     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0376547     Medline TA:  Experientia     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  1179-80     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aflatoxins / pharmacology*,  toxicity
Animals
Cold Temperature*
Drug Resistance
Liver / anatomy & histology,  drug effects*
Male
Rats
Chemical
Reg. No./Substance:
0/Aflatoxins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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