| Resistance and aerobic exercise protects against acute endothelial impairment induced by a single exposure to hypertension during exertion. | |
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MedLine Citation:
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PMID: 21252216 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Resistance and aerobic exercise is recommended for cardiovascular health and disease prevention. However, the accompanying increase in arterial pressure during resistance exercise may be detrimental to vascular health. This study tests the vascular benefits of aerobic compared with resistance exercise on preventing impaired vascular function induced by a single weight lifting session that is associated with acute hypertension. Healthy, lean sedentary (SED) subjects, weight lifters, runners (>15 miles/wk), and cross trainers (chronic aerobic and resistance exercisers), underwent a single progressive leg press weight lifting session with blood pressure measurements. Brachial artery flow-mediated vasodilation (FMD; an index of arterial endothelial function) was determined using ultrasonography immediately before and after weight lifting. Sublingual nitroglycerin (0.4 mg) was used to determine endothelium-independent dilation after weight lifting. All subjects were normotensive with similar blood pressure responses during exercise. Baseline FMD was lower in runners (5.4 ± 0.5%; n = 13) and cross trainers (4.44 ± 0.3%; n = 13) vs. SED (8.5 ± 0.8%; n = 13; P = 0.037). Brachial FMD improved in conditioned weight lifters (to 8.8 ± 0.9%; P = 0.007) and runners (to 7.6 ± 0.6%; P < 0.001) but not cross trainers (to 5.3 ± 0.6%; P = NS) after acute hypertension. FMD was decreased in SED (to 5.7 ± 0.4%; P = 0.019). Dilation to nitroglycerin was similar among groups. These data suggest that endothelial responses are maintained after exposure to a single bout of weight lifting in resistance and aerobic athletes. Resistance and aerobic exercise may confer similar protection against acute vascular insults such as exertional hypertension. |
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Authors:
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Shane A Phillips; Emon Das; Jingli Wang; Kirkwood Pritchard; David D Gutterman |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2011-01-20 |
Journal Detail:
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Title: Journal of applied physiology (Bethesda, Md. : 1985) Volume: 110 ISSN: 1522-1601 ISO Abbreviation: J. Appl. Physiol. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-04-13 Completed Date: 2011-08-15 Revised Date: 2012-04-02 |
Medline Journal Info:
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Nlm Unique ID: 8502536 Medline TA: J Appl Physiol Country: United States |
Other Details:
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Languages: eng Pagination: 1013-20 Citation Subset: IM |
Affiliation:
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Department of Physical Therapy, University of Illinois at Chicago, Chicago, Illinois, USA. shanep@uic.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Analysis of Variance Blood Pressure / physiology Brachial Artery / physiology, ultrasonography Endothelium, Vascular / physiology*, ultrasonography Exercise / physiology* Humans Hypertension / physiopathology*, ultrasonography Male Muscle, Skeletal / physiology Regional Blood Flow / physiology Vasodilation / physiology |
| Grant Support | |
ID/Acronym/Agency:
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K23-HL-85614/HL/NHLBI NIH HHS; M01-RR00058/RR/NCRR NIH HHS; UL1RR029879/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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