Document Detail

Resin hemoperfusion in chloroquine poisoning.
MedLine Citation:
PMID:  7184999     Owner:  NLM     Status:  MEDLINE    
A 46-year-old woman was admitted after ingestion of 10 g chloroquine phosphate. The patient's clinical condition deteriorated with characteristic ECG changes, low blood pressure, and respiratory depression. Resin hemoperfusion (HP) was started 4.5 h after admission at a flow of 250 mL/min for 4 h. Clearance over the resin column was 136 mL/min. Although the patient rapidly improved, a total of no more than 200 mg (2%) was removed. Total body clearance of chloroquine was increased by only 5% during HP. Treatment should therefore be directed toward aggressive supportive therapy rather than techniques to increase elimination.
A Heath; J Ahlmén; T Mellstrand; I Wickström
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of toxicology. Clinical toxicology     Volume:  19     ISSN:  0731-3810     ISO Abbreviation:  J. Toxicol. Clin. Toxicol.     Publication Date:  1982 Dec 
Date Detail:
Created Date:  1983-09-23     Completed Date:  1983-09-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8213460     Medline TA:  J Toxicol Clin Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1067-71     Citation Subset:  AIM; IM    
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MeSH Terms
Chloroquine / blood,  poisoning*
Middle Aged
Reg. No./Substance:
0/Polystyrenes; 0/Polyvinyls; 37380-42-0/XAD-4 resin; 54-05-7/Chloroquine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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