Document Detail


Residues of polychlorinated biphenyls in edible fish of the Adriatic Sea: assessment of human exposure.
MedLine Citation:
PMID:  17995758     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Food consumption is an important route of human exposure to polychlorinated biphenyls (PCBs). To assess the potential health risks associated with these contaminants due to fish consumption, the muscle tissue of edible species of fish was analyzed. Contamination levels among the different species varied from 134 to 1210 ng/g lipid weight. Isomer-specific analysis revealed a profile dominated by hexa- (57.9% to 82.9%) and pentachlorobiphenyls (10.3% to 23.9%), followed by hepta- (9.0% to 19.2%) and tetrachlorobiphenyls (0.7% to 17.5%). Other congeners, including those with less than 4 or more than 9 chlorine atoms, were below the instrumental limit of detection in all samples. Risk evaluation for human health was carried out by comparing the experimental data with the new European Commission legal level and a new approach proposed by the U.S. EPA to protect population-segments who repeatedly consume fish. The dietary intake of PCBs, as WHO-TEQ per kg body weight (b.w.), was below 8 pg TEQ/kg body weight/week, while the new EPA approach suggested that the chronic effects do not represent any type of danger for human health, while the possible rise in the carcinogenic risk connected with consumption of some type of fish is more worrisome.
Authors:
M M Storelli; G Barone; G O Marcotrigiano
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of food science     Volume:  72     ISSN:  1750-3841     ISO Abbreviation:  J. Food Sci.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-11-12     Completed Date:  2008-01-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0014052     Medline TA:  J Food Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  C183-7     Citation Subset:  IM    
Affiliation:
Pharmacological-Biological Dept., Chemistry and Biochemistry Section, Medicine Veterinary Faculty, Univ. of Bari, Strada prov. le per Casamassima, km, 3, 70010 Valenzano, (BA), Italy. m.m.storelli@veterinaria.uniba.it <m.m.storelli@veterinaria.uniba.it>
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue / chemistry
Animals
Environmental Pollutants / analysis*
Fishes*
Food Contamination / analysis*
Gas Chromatography-Mass Spectrometry
Hexanes
Humans
Muscle, Skeletal / chemistry*
Pesticide Residues / analysis*
Polychlorinated Biphenyls / analysis*
Reference Standards
Risk Factors
World Health Organization
Chemical
Reg. No./Substance:
0/Environmental Pollutants; 0/Hexanes; 0/Pesticide Residues; 0/Polychlorinated Biphenyls

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