Document Detail


Residue levels of organochlorinated insecticides in breast milk: a preliminary report from Al-Kharj, Saudi Arabia.
MedLine Citation:
PMID:  9490319     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Breast milk samples obtained from 115 mothers residing in Al-Kharj area, Saudi Arabia, were quantified by gas chromatography and confirmed by gas chromatography-mass spectrometry for lindane, heptachlor, heptachlor epoxide, dieldrin, endrin, p,p-DDE, p,p-DDD, and p,p-DDT. The results showed that 80.9% of the samples contained p,p-DDT, 93.9% p,p-DDE, and 74.8% p,p-DDD. Whereas lindane, heptachlor, heptachlor-epoxide, dieldrin, and endrin were found in 23.5, 20.9, 36.5, 48.7, and 32.2% screened samples, respectively. Results of this survey clearly show that infants were exposed to organochlorinated pesticides. Although the levels of organochlorinated pesticides reported here are lower than those reported from several other countries, the maximum daily intakes of those pesticides exceeded the WHO/UNEP Acceptable Daily Intakes for a 5-kg infant. This finding warrants further research to determine the magnitude of the problem in Saudi Arabia. As there is a bulk of literature that highlights the adverse health effects of organochlorinated pesticides on children and infants, it would be advantageous to establish a regular organochlorinated pesticides monitoring program.
Authors:
I Al-Saleh; A Echeverria-Quevedo; S Al-Dgaither; R Faris
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer     Volume:  17     ISSN:  0731-8898     ISO Abbreviation:  J. Environ. Pathol. Toxicol. Oncol.     Publication Date:  1998  
Date Detail:
Created Date:  1998-03-05     Completed Date:  1998-03-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8501420     Medline TA:  J Environ Pathol Toxicol Oncol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  37-50     Citation Subset:  IM    
Affiliation:
Biological and Medical Research Department, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Chromatography, Gas
Female
Gas Chromatography-Mass Spectrometry
Humans
Hydrocarbons, Chlorinated*
Insecticides / analysis*
Lactation
Middle Aged
Milk, Human / chemistry*
Pesticide Residues / chemistry*
Saudi Arabia
Chemical
Reg. No./Substance:
0/Hydrocarbons, Chlorinated; 0/Insecticides; 0/Pesticide Residues

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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