Document Detail

Residuals for proportional hazards models with interval-censored survival data.
MedLine Citation:
PMID:  10877306     Owner:  NLM     Status:  MEDLINE    
We develop diagnostic tools for use with proportional hazards models for interval-censored survival data. We propose counterparts to the Cox-Snell, Lagakos (or martingale), deviance, and Schoenfeld residuals. Many of the properties of these residuals carry over to the interval-censored case. In particular, the interval-censored versions of the Lagakos and Schoenfeld residuals may be derived as components of suitable score statistics. The Lagakos residuals may be used to check regression relationships, while the Schoenfeld residuals can help to detect nonproportional hazards in semiparametric models. The methods apply to parametric models and to the semiparametric model with discrete observation times.
C P Farrington
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biometrics     Volume:  56     ISSN:  0006-341X     ISO Abbreviation:  Biometrics     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-10-10     Completed Date:  2000-10-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370625     Medline TA:  Biometrics     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  473-82     Citation Subset:  IM; X    
Department of Statistics, The Open University, Milton Keynes, UK.
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MeSH Terms
Acquired Immunodeficiency Syndrome / drug therapy,  immunology,  mortality
Anti-HIV Agents / therapeutic use
Biometry / methods
Breast Neoplasms / drug therapy,  mortality,  radiotherapy
CD4 Lymphocyte Count
Models, Statistical
Proportional Hazards Models*
Regression Analysis
Survival Analysis*
Time Factors
Zidovudine / therapeutic use
Reg. No./Substance:
0/Anti-HIV Agents; 30516-87-1/Zidovudine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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