Document Detail


Residual dipolar couplings as new conformational restraints in isotropically 13C-enriched oligosaccharides.
MedLine Citation:
PMID:  9771907     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report the measurement of residual dipolar couplings for l3C-enriched NeuNAcalpha2-3Galbeta1-4Glc in a dilute liquid-crystalline medium. These couplings provide long-range conformational restraints that hitherto have not been available for oligosaccharides. We utilise these restraints in dynamical simulated annealing calculations, which support current models of the solution behaviour of the trisaccharide.
Authors:
G R Kiddle; S W Homans
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  FEBS letters     Volume:  436     ISSN:  0014-5793     ISO Abbreviation:  FEBS Lett.     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-10-28     Completed Date:  1998-10-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0155157     Medline TA:  FEBS Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  128-30     Citation Subset:  IM    
Affiliation:
Centre for Biomolecular Sciences, University of St. Andrews, FIFE, UK.
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MeSH Terms
Descriptor/Qualifier:
Carbohydrate Conformation
Carbohydrate Sequence
Computer Simulation
G(M3) Ganglioside / chemistry*
Magnetic Resonance Spectroscopy
Models, Molecular*
Molecular Sequence Data
Oligosaccharides / chemistry*
Trisaccharides / chemistry
Chemical
Reg. No./Substance:
0/G(M3) Ganglioside; 0/Oligosaccharides; 0/Trisaccharides

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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