Document Detail

Residual Activity of Chelating Agents and their Combinations with Cetrimide on Root Canals Infected with Enterococcus faecalis.
MedLine Citation:
PMID:  22595119     Owner:  NLM     Status:  In-Data-Review    
INTRODUCTION: The use of chelating agents in endodontic treatment is required to remove the smear layer and to achieve better disinfection within the root canal system. The aim of this study was to evaluate the residual antimicrobial activity of 17% ethylenediaminetetraacetic acid (EDTA), 7% maleic acid (MA), and 10% lactic acid (LA) alone and combined with 0.2% cetrimide (CTR) on infected root canals with Enterococcus faecalis.
METHODS: Biofilms of E. faecalis were grown in uniradicular roots for 4 weeks. After preparation the roots were randomly divided into 6 groups (n = 15) according to the final irrigation regimen as follows: 5 mL of 17% EDTA; 5 mL of 17% EDTA + 0.2% CTR; 5 mL of 7% MA; 5 mL of 7% MA + 0.2% CTR; 5 mL of 10% LA; and 5 mL of 10% LA + 0.2% CTR. Samples were collected for 60 days to denote the presence of bacterial growth. Fisher and Pearson χ(2) tests were applied to compare the percentages of specimens without E. faecalis regrowth at all the time periods.
RESULTS: There were significant differences in bacterial regrowth between the groups with and without CTR. There were not significant differences over time among the 3 groups with CTR or among the 3 without CTR.
CONCLUSIONS: The residual activity against E. faecalis of 7% MA + 0.2% CTR, 17% EDTA + 0.2% CTR, and 10% LA + 0.2% CTR was greater than the use of chelating agents alone.
Carmen María Ferrer-Luque; Amanda Conde-Ortiz; María Teresa Arias-Moliz; Mariano José Valderrama; Pilar Baca
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Publication Detail:
Type:  Journal Article     Date:  2012-02-24
Journal Detail:
Title:  Journal of endodontics     Volume:  38     ISSN:  1878-3554     ISO Abbreviation:  J Endod     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-05-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7511484     Medline TA:  J Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  826-8     Citation Subset:  D    
Copyright Information:
Copyright © 2012 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.
Department of Operative Dentistry, School of Dentistry, University of Granada, Granada, Spain.
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