Document Detail


Residential magnetic fields as a risk factor for childhood acute leukaemia: results from a German population-based case-control study.
MedLine Citation:
PMID:  11267988     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Our objective was to investigate whether exposure to residential power-frequency (50 Hz) magnetic fields above 0.2 microT increases a child's risk of leukaemia and to confirm or reject a finding from a previous German study on this topic, which reported increased leukaemia risk with exposure to stronger magnetic fields during the night. A population-based case-control study was used, covering the whole of the former West Germany. Residential magnetic fields were measured over 24 hr for 514 children with acute leukaemia identified by the German Childhood Cancer Registry and 1,301 control children taken from population registration files. Magnetic fields above 0.2 microT were relatively rare in Germany (only 1.5% of the study population). Childhood leukaemia and 24 hr median magnetic fields were only weakly related (OR = 1.55, 95% CI 0.65-3.67). A significant association was seen between childhood leukaemia and magnetic field exposure during the night (OR = 3.21, 95% CI 1.33-7.80). A dose-response-relationship was observed after combining the data of all German studies on magnetic fields and childhood leukaemia. The evidence for an association between childhood leukaemia and magnetic field exposure in our study comes from a measure of exposure during the night. Despite the large size of our study, the results are based on small numbers of exposed children. If the observed association stands, the effect on a population level in Germany would be small.
Authors:
J Schüz; J P Grigat; K Brinkmann; J Michaelis
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of cancer. Journal international du cancer     Volume:  91     ISSN:  0020-7136     ISO Abbreviation:  Int. J. Cancer     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-27     Completed Date:  2001-04-19     Revised Date:  2007-07-24    
Medline Journal Info:
Nlm Unique ID:  0042124     Medline TA:  Int J Cancer     Country:  United States    
Other Details:
Languages:  eng     Pagination:  728-35     Citation Subset:  IM    
Copyright Information:
Copyright 2001 Wiley-Liss, Inc.
Affiliation:
Institute for Medical Statistics and Documentation, University of Mainz, Mainz, Germany. schuez@imsd.uni-mainz.de
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Case-Control Studies
Child
Child, Preschool
Dose-Response Relationship, Radiation
Electromagnetic Fields / adverse effects*
Female
Germany
Humans
Infant
Infant, Newborn
Leukemia / epidemiology*,  etiology*
Leukemia, Radiation-Induced / epidemiology,  etiology
Male
Odds Ratio
Risk Factors
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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