Document Detail


Reserved higher vagal tone under acute hypoxia in Tibetan adolescents with long-term migration to sea level.
MedLine Citation:
PMID:  12047802     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Tibetans are known as one of the largest and oldest high-altitude natives in the world and are among the best high-altitude-adapted ethnic groups. They exhibit greater vagal tone and less sympathetic stimulation than acclimatized lowlanders at high altitudes. Whether young native Tibetans who had spent long-term residence (more than 3 years) at sea level still reserved their unique autonomic characteristics was the main aim of this study. Heart rate variability (HRV) of 10 native young Tibetan male students and 12 Han counterparts were measured at resting supine position at sea level and 1 h after ascent to 3,700 m in a hypobaric chamber (PO(2) = 13.4 kPa). At sea level, Tibetans showed lower heart rate (HR) and greater HRV. At 3,700 m, the increase of HR was greater in the Hans than in the Tibetans, and the HRV was significantly diminished in the Han group but not in the Tibetan group. The results suggested that Tibetans had a greater parasympathetic dominance over the heart at rest, and acute moderate (3,700 m) hypoxia did not influence their HRV significantly, but it did on the Han subjects. We concluded that the long-term residence of the Tibetans at sea level did not change their unique characteristics of the autonomic systems.
Authors:
Jianguo Zhuang; Haifeng Zhu; Zhaonian Zhou
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Japanese journal of physiology     Volume:  52     ISSN:  0021-521X     ISO Abbreviation:  Jpn. J. Physiol.     Publication Date:  2002 Feb 
Date Detail:
Created Date:  2002-06-05     Completed Date:  2002-10-23     Revised Date:  2007-03-21    
Medline Journal Info:
Nlm Unique ID:  2985184R     Medline TA:  Jpn J Physiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  51-6     Citation Subset:  IM    
Affiliation:
Shanghai Institute of Physiology, Chinese Academy of Sciences, Shanghai 200031, China.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adolescent
Altitude*
Anoxia / physiopathology*
Asian Continental Ancestry Group
Emigration and Immigration*
Heart Rate
Humans
Male
Parasympathetic Nervous System / physiopathology
Tibet
Time Factors
Vagus Nerve / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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