| Resection of pheochromocytoma under inferior vena caval isolation and extracorporeal charcoal hemoperfusion. | |
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MedLine Citation:
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PMID: 9749859 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Resection of pheochromocytoma is associated with potential risks of hypertensive crises and serious arrhythmias due to massive release of catecholamines from the tumor. We report our surgical experience with complete inferior vena caval isolation and extracorporeal charcoal hemoperfusion (IVCI-CHP), which were performed to prevent systemic exposure to catecholamines during surgical manipulation. The IVCI-CHP significantly reduced the postfilter and systemic catecholamine levels compared with the prefilter levels (P<.01), indicating substantial catecholamine extraction (>90%) by the CHP filter. Reflecting the reduction of systemic exposure to catecholamines during IVCI-CHP, the patient's blood pressures were markedly stable. Our findings suggest that IVCI-CHP may be useful to minimize the risk of hypertensive crises during surgical manipulation of pheochromocytoma, by preventing systemic exposure to high levels of circulatory catecholamines. |
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Authors:
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M Tominaga; Y Ku; T Iwasaki; S Muramatsu; Y Kuroda; Y Shima; Y Takao; H Obara |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Archives of surgery (Chicago, Ill. : 1960) Volume: 133 ISSN: 0004-0010 ISO Abbreviation: Arch Surg Publication Date: 1998 Sep |
Date Detail:
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Created Date: 1998-10-15 Completed Date: 1998-10-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9716528 Medline TA: Arch Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1016-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Surgery I, Faculty of Medicine, Kobe University, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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surgery* Adult Catecholamines / blood Charcoal Female Hemoperfusion / methods* Humans Hypertension / prevention & control Intraoperative Complications / prevention & control Pheochromocytoma / blood, surgery* Vena Cava, Inferior |
| Chemical | |
Reg. No./Substance:
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0/Catecholamines; 16291-96-6/Charcoal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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