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Resecting without detecting the lesion in extratemporal lobe epilepsy?
MedLine Citation:
PMID:  24532278     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Nonlesional extratemporal lobe epilepsy (ETLE) often persists following resection of the site of ictal onset, localized with definitive intracranial EEG recordings.(1,2) In lesional ETLE, however, lesionectomy with resection of a single electrophysiologically defined ictal onset (ictogenic) zone often stops seizures immediately and permanently.(1,2) In temporal lobe epilepsy (TLE), a single ictogenic site can be resected, either with an accompanying lesion or in the absence of an MRI-detected lesion, and is a highly efficacious epilepsy therapy.(2) Efforts to increase surgical efficacy in nonlesional ETLE have focused on localization by functional imaging to substitute for lesion localization by structural imaging.
Authors:
Thomas R Henry
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-14
Journal Detail:
Title:  Neurology     Volume:  -     ISSN:  1526-632X     ISO Abbreviation:  Neurology     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-2-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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