Document Detail

Researches for diagnostic neuroradiology focusing on signals and shapes.
MedLine Citation:
PMID:  22277432     Owner:  NLM     Status:  In-Data-Review    
MRI is one of essential tools for neurological diagnosis and useful for assessing contrast differences between lesions and normal tissues and for assessing morphological features of lesions. Here, I introduce published neuroradiological researches conducted in my hospital, especially focusing on features of "signals" and "shapes" of lesions. First, as regards "signals", putaminal T(1)-hyperintensity is helpful for diagnosing multiple system atrophy, and it is more useful for discriminating multiple system atrophy from Parkinson disease and progressive supranuclear palsy than putaminal T(2)-hyperintensity rim or putaminal T(2)-hypointensity. Linear T(2)-hyperintensity along the medial margin of the globus pallidus is helpful for diagnosis Machado-Joseph disease. Second, as regards "shapes", posterolateral putaminal linearization is a useful finding indicating putaminal atrophy which is a main feature of multiple system atrophy. Flattened facial colliculus/fourth ventricular floor is helpful for differentiating Machado-Joseph disease from dentatorublopallidoluysian atrophy and SCA6. A contrast enhancement pattern called "cloud-like enhancement" is specific for neuromyelitis optica comparing with multiple sclerosis. In conclusion, all of these MRI features are easy to recognize and useful for diagnosing patients in daily clinical settings. Careful but simple observation of lesions focusing on "signals" or "shapes" may lead to develop new MRI findings which improve our diagnostic abilities.
Shoichi Ito
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Rinshō shinkeigaku = Clinical neurology     Volume:  51     ISSN:  0009-918X     ISO Abbreviation:  Rinsho Shinkeigaku     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2012-01-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0417466     Medline TA:  Rinsho Shinkeigaku     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  951-4     Citation Subset:  IM    
Office of Medical Education, School of Medicine, Chiba University.
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