Document Detail

Research in patients with heart failure: challenges in recruitment.
MedLine Citation:
PMID:  18450677     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Published studies of patients with heart failure may not include details about the challenges in the recruitment process. OBJECTIVES: To describe the recruitment process during the first 18 months of a study being conducted to evaluate cognitive deficits in patients with chronic heart failure. METHODS: Details of the recruitment process are described for 2 clinic sites. RESULTS: A total of 4,027 echocardiograms were screened at site 1 to evaluate eligibility. Of the 161 patients eligible, 61 (38%) were invited to participate, and 29 of the 61 (48%) completed the study. At site 2, four hundred thirty-seven medical records of patients were screened, resulting in 163 eligible patients (37%). The staff invited 70 of the 163 patients (43%) to participate, and 52 of the 70 (74%) completed the study. The refusal rate was 23% at site 1 and 21% at site 2. CONCLUSIONS: Successful recruitment in studies involving patients with heart failure often requires screening of a large group of patients.
Susan J Pressler; Usha Subramanian; Rose Mary Shaw; Leslie E Meyer; Klarisa Stoudemire; Irmina Gradus-Pizlo
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Publication Detail:
Type:  Journal Article; Multicenter Study; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  American journal of critical care : an official publication, American Association of Critical-Care Nurses     Volume:  17     ISSN:  1062-3264     ISO Abbreviation:  Am. J. Crit. Care     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-05-02     Completed Date:  2008-07-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211547     Medline TA:  Am J Crit Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  198-203     Citation Subset:  IM; N    
Indiana University School of Nursing in Indianapolis, IN, USA.
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MeSH Terms
Aged, 80 and over
Biomedical Research
Clinical Trials as Topic / methods*
Cognition Disorders / etiology*
Heart Failure / complications*,  diagnosis
Middle Aged
Patient Selection*
Refusal to Participate*
United States
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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