Document Detail

Research Spotlight: Nanomedicines for HIV therapy.
MedLine Citation:
PMID:  23343155     Owner:  NLM     Status:  In-Data-Review    
Heterogeneity in response to HIV treatments has been attributed to several causes including variability in pharmacokinetic exposure. Nanomedicine applications have a variety of advantages compared with traditional formulations, such as the potential to increase bioavailability and specifically target the site of action. Our group is focusing on the development of nanoformulations using a closed-loop design process in which nanoparticle optimization (disposition, activity and safety) is a continuous process based on experimental pharmacological data from in vitro and in vivo models. Solid drug nanoparticles, polymer-based drug-delivery carriers as well as nanoemulsions are nanomedicine options with potential application to improve antiretroviral deployment.
Marco Siccardi; Philip Martin; Tom O McDonald; Neill J Liptrott; Marco Giardiello; Steve Rannard; Andrew Owen
Related Documents :
24277245 - Nephelometric immunoassay for therapeutic drug level monitoring.
23333885 - Current status and future prospects of drug eluting stents for restenosis / sadašnjost...
24734245 - Digging up the human genome: current progress in deciphering adverse drug reactions.
23422415 - Drug-resistant tuberculosis.
17376605 - Redrawing papez' circuit: a theory about how acute stress becomes chronic and causes di...
20488845 - Morbidity associated with mdma (ecstasy) abuse: a survey of emergency department admiss...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Therapeutic delivery     Volume:  4     ISSN:  2041-5990     ISO Abbreviation:  Ther Deliv     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101538870     Medline TA:  Ther Deliv     Country:  England    
Other Details:
Languages:  eng     Pagination:  153-6     Citation Subset:  IM    
Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Conference report: 1st medicon valley inhalation symposium.
Next Document:  Nanomedicine for uterine leiomyoma therapy.