Document Detail

Rescue percutaneous coronary intervention for failed thrombolysis: results from a district general hospital.
MedLine Citation:
PMID:  12151685     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the outcome of a policy of emergency percutaneous coronary intervention (PCI) in patients with acute myocardial infarction and electrocardiographic (ECG) evidence of failed reperfusion after thrombolysis. DESIGN: Observational study. SETTING: District general hospital. PATIENTS: A total of 109 consecutive patients with acute myocardial infarction who underwent emergency angiography and angioplasty for failed reperfusion diagnosed on the basis of standard ECG criteria. MAIN OUTCOME MEASURES: In-hospital mortality; death, infarct territory reinfarction, and reintervention by PCI or coronary artery bypass graft (CABG) during follow up; in-lab resource utilisation. RESULTS: At initial angiography, 76 patients had Thrombolysis in Myocardial Infarction (TIMI) trial 0/1 flow and 33 had TIMI 2/3 flow. Fourteen patients were in cardiogenic shock. TIMI 3 flow was established or maintained in 93 patients (85%). Overall in-hospital mortality was 9%. It was 3% in non-shock patients, 50% in shocked patients, and 40% when the procedure was unsuccessful (TIMI 0/1 flow post-procedure). Over a mean follow up of 30 months (>12 months of follow up in all patients) there were 19 further events (one death, five reinfarctions, and 13 revascularisations (nine CABG and four PCI)). The cost of rescue PCI was not significantly higher than comparable elective interventions. CONCLUSION: A policy of emergency angiography and PCI for failed reperfusion in acute myocardial infarction can be carried out in a hospital without on-site surgical backup with good medium term clinical outcomes.
K P Balachandran; J Miller; A C H Pell; B D Vallance; K G Oldroyd
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Postgraduate medical journal     Volume:  78     ISSN:  0032-5473     ISO Abbreviation:  Postgrad Med J     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-08-01     Completed Date:  2002-09-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0234135     Medline TA:  Postgrad Med J     Country:  England    
Other Details:
Languages:  eng     Pagination:  330-4     Citation Subset:  IM    
Lanarkshire Cardiac Catheterisation Laboratories, Hairmyres Hospital, Eaglesham Road, East Kilbride G75 8RG, UK.
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MeSH Terms
Angioplasty, Transluminal, Percutaneous Coronary*
Coronary Angiography*
Coronary Artery Bypass
Middle Aged
Myocardial Infarction / drug therapy,  mortality,  therapy*
Prospective Studies
Retrospective Studies
Thrombolytic Therapy*
Treatment Failure
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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