Document Detail

Rescue high frequency oscillation in neonates with acute respiratory failure.
MedLine Citation:
PMID:  21555797     Owner:  NLM     Status:  MEDLINE    
The aim was to study the efficacy of rescue High Frequency Oscillatory Ventilation (HFOV) in improving the oxygenation and ventilation in neonates with acute respiratory failure after failing Conventional Mechanical Ventilation (CMV). Primary outcome was short term oxygenation, lung recruitment, and ventilation and secondary outcome studied was survival. 675 babies were ventilated and 97 of them received HFOV. HFOV significantly improved oxygenation index, alveolar-arterial oxygen gradient, pH, PCO2, PO2 and caused better lung recruitment within 2 hours. Fifty seven babies (58.77%) survived and the mortality was more in <28 weeks, babies with pulmonary hemorrhage, sepsis and CDH.
Preetham Kumar Poddutoor; Dinesh Kumar Chirla; Kapil Sachane; Farhan A R Shaik; Alla Venkatlakshmi
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Publication Detail:
Type:  Journal Article     Date:  2011-02-28
Journal Detail:
Title:  Indian pediatrics     Volume:  48     ISSN:  0974-7559     ISO Abbreviation:  Indian Pediatr     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-07-11     Completed Date:  2011-11-09     Revised Date:  2011-11-21    
Medline Journal Info:
Nlm Unique ID:  2985062R     Medline TA:  Indian Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  467-70     Citation Subset:  IM    
Rainbow Childrens Hospital and Perinatal Centre, Banjara Hills, Hyderabad, India.
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MeSH Terms
Blood Gas Analysis
High-Frequency Ventilation / methods*
Infant, Newborn
Oxygen / blood
Respiratory Distress Syndrome, Newborn / blood,  therapy*
Respiratory Insufficiency / blood,  therapy*
Reg. No./Substance:

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