| Requirements for Parkinson's disease pharmacotherapy from the patients' perspective: a questionnaire-based survey. | |
| | |
MedLine Citation:
|
PMID: 22686959 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Abstract Objective: Knowledge of patients' treatment needs is an important requirement for comprehensive long-term patient care. The objective of this investigation was to assess the requirements of patients with Parkinson's disease (PD) regarding pharmacotherapy. Methods: A total of 17,500 members of the German Parkinson Association were given the opportunity to anonymously answer a questionnaire about their health-related quality of life, PD pharmacotherapy and their improvement suggestions for new PD medication. Results: Answers from 6351 patients were available for analysis. The majority (87.2%) of patients were older than 60 years; 88.9% had been diagnosed with PD for longer than 3 years and 84.4% selected one of the three most severe categories (categories 1-3 on a 6-point scale) when rating the impact of PD on their quality of life. Symptoms that were regarded as very important for improvement with pharmacotherapy included motor fluctuations (66.3%), early morning akinesia (55.4%) and sleep disturbances (43.5%). Properties of a new PD medication that were rated as very important included continuous drug delivery over 24 hours (66.6%) and 24-hour symptom control (55.8%). The majority of patients used physicians (84.2%) and/or self-help groups (69.4%) to obtain information about PD. Topics of particular interest included comorbid diseases (78.3%), mobility and exercise (77.3%) and research (53%). Conclusion: PD has a major impact on patients' quality of life. From the patient's perspective, PD pharmacotherapy needs to address a range of symptoms including not only motor symptoms, but also nonmotor symptoms such as sleep disturbances. In selecting the most appropriate treatment regimen, patient preference is an important consideration. |
| | |
Authors:
|
Ullrich Wüllner; Gerd Fuchs; Nicole Reketat; Olaf Randerath; Jan Kassubek |
Related Documents
:
|
21558859 - Descriptive analysis of oxygen use in australian emergency departments. 19827989 - Therapy of community-acquired acute bacterial meningitis: the clock is running. 2845779 - Oral fluconazole as suppressive therapy of disseminated cryptococcosis in patients with... 956879 - Restricted fluid intake. rational management of the neurosurgical patient. 21817969 - The impact of discharging minimally injured trauma patient: does age play a role in tra... 12458049 - Increased expression of the th1-inducing cytokines interleukin-12 and interleukin-18 in... 21558859 - Descriptive analysis of oxygen use in australian emergency departments. 20373909 - Domiciliary experience of the target inhalation mode (tim) breathing maneuver in patien... 16908219 - Treatment of patients with coexisting epileptic and nonepileptic seizures. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-6-11 |
Journal Detail:
|
Title: Current medical research and opinion Volume: - ISSN: 1473-4877 ISO Abbreviation: - Publication Date: 2012 Jun |
Date Detail:
|
Created Date: 2012-6-12 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0351014 Medline TA: Curr Med Res Opin Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Myopathy during statin-therapy in the daily practice of an outpatient cardiology clinic: prevalence,...
Next Document: Behavioral Characteristics of Internet Gamblers Who Trigger Corporate Responsible Gambling Intervent...