Document Detail


Reprogramming a broken heart.
MedLine Citation:
PMID:  22770235     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Fibrosis resulting from cardiac injury presents a major challenge to restoring heart function after myocardial infarction. Two recent papers in Nature report successful in vivo reprogramming of fibroblasts to cardiomyocytes in injured mouse hearts (Qian et al., 2012; Song et al., 2012), resulting in improved cardiac function and reduced scar formation.
Authors:
Emil M Hansson; Kenneth R Chien
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell stem cell     Volume:  11     ISSN:  1875-9777     ISO Abbreviation:  Cell Stem Cell     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-09     Completed Date:  2012-11-06     Revised Date:  2013-03-21    
Medline Journal Info:
Nlm Unique ID:  101311472     Medline TA:  Cell Stem Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3-4     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 01238, USA.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
U01 HL100408/HL/NHLBI NIH HHS
Comments/Corrections
Comment On:
Nature. 2012 May 31;485(7400):593-8   [PMID:  22522929 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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