| Reproductive genetics and today's patient options: prenatal diagnosis. | |
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MedLine Citation:
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PMID: 9615567 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rapid and safe prenatal diagnosis has become the standard of care in high-risk pregnancy. The safety and reliability of prenatal diagnosis by mid-trimester amniocentesis and first-trimester chorionic villus sampling (CVS) are reviewed, and accepted medical indications for referral are defined for both procedures. Techniques for evaluating the fetus for abnormality including amniocentesis, CVS, ultrasound, percutaneous umbilical blood sampling, fetal biopsy, amniotic fluid alpha-fetoprotein analysis, and maternal serum screening are described. The need for appropriate prenatal genetic counseling before any diagnostic modality is emphasized. |
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Authors:
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J P Willner |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Mount Sinai journal of medicine, New York Volume: 65 ISSN: 0027-2507 ISO Abbreviation: Mt. Sinai J. Med. Publication Date: 1998 May |
Date Detail:
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Created Date: 1998-08-07 Completed Date: 1998-08-07 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0241032 Medline TA: Mt Sinai J Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 173-7 Citation Subset: E; IM |
Affiliation:
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Department of Human Genetics, Mount Sinai School of Medicine, New York, NY 10029, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amniocentesis Amniotic Fluid / chemistry Biopsy / methods Chorionic Villi Sampling Female Fetal Blood / chemistry Fetus / pathology Genetic Counseling Genetic Diseases, Inborn / diagnosis*, pathology Genetic Techniques Humans Pregnancy Pregnancy, High-Risk Prenatal Diagnosis* Ultrasonography, Prenatal alpha-Fetoproteins / analysis |
| Chemical | |
Reg. No./Substance:
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0/alpha-Fetoproteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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