Document Detail

Reproductive genetics and today's patient options: prenatal diagnosis.
MedLine Citation:
PMID:  9615567     Owner:  NLM     Status:  MEDLINE    
Rapid and safe prenatal diagnosis has become the standard of care in high-risk pregnancy. The safety and reliability of prenatal diagnosis by mid-trimester amniocentesis and first-trimester chorionic villus sampling (CVS) are reviewed, and accepted medical indications for referral are defined for both procedures. Techniques for evaluating the fetus for abnormality including amniocentesis, CVS, ultrasound, percutaneous umbilical blood sampling, fetal biopsy, amniotic fluid alpha-fetoprotein analysis, and maternal serum screening are described. The need for appropriate prenatal genetic counseling before any diagnostic modality is emphasized.
J P Willner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Mount Sinai journal of medicine, New York     Volume:  65     ISSN:  0027-2507     ISO Abbreviation:  Mt. Sinai J. Med.     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-08-07     Completed Date:  1998-08-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0241032     Medline TA:  Mt Sinai J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  173-7     Citation Subset:  E; IM    
Department of Human Genetics, Mount Sinai School of Medicine, New York, NY 10029, USA.
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MeSH Terms
Amniotic Fluid / chemistry
Biopsy / methods
Chorionic Villi Sampling
Fetal Blood / chemistry
Fetus / pathology
Genetic Counseling
Genetic Diseases, Inborn / diagnosis*,  pathology
Genetic Techniques
Pregnancy, High-Risk
Prenatal Diagnosis*
Ultrasonography, Prenatal
alpha-Fetoproteins / analysis
Reg. No./Substance:

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