| Reproductive consequences of developmental phytoestrogen exposure. | |
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MedLine Citation:
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PMID: 22223686 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Phytoestrogens, estrogenic compounds derived from plants, are ubiquitous in human and animal diets. These chemicals are generally much less potent than estradiol but act via similar mechanisms. The most common source of phytoestrogen exposure to humans is soybean-derived foods that are rich in the isoflavones genistein and daidzein. These isoflavones are also found at relatively high levels in soy-based infant formulas. Phytoestrogens have been promoted as healthy alternatives to synthetic estrogens and are found in many dietary supplements. The aim of this review is to examine the evidence that phytoestrogen exposure, particularly in the developmentally sensitive periods of life, has consequences for future reproductive health. |
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Authors:
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Wendy N Jefferson; Heather B Patisaul; Carmen J Williams |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Review Date: 2012-01-05 |
Journal Detail:
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Title: Reproduction (Cambridge, England) Volume: 143 ISSN: 1741-7899 ISO Abbreviation: Reproduction Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-03-19 Completed Date: 2012-07-24 Revised Date: 2013-04-01 |
Medline Journal Info:
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Nlm Unique ID: 100966036 Medline TA: Reproduction Country: England |
Other Details:
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Languages: eng Pagination: 247-60 Citation Subset: IM |
Affiliation:
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Reproductive Medicine Group, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, National Institutes of Health, NIEHS/NIH/DHHS, MD E4-05, Research Triangle Park, North Carolina 27709, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Child Development / drug effects* Diet Humans Infant Infant Food / adverse effects Infant Formula / chemistry Infant, Newborn Phytoestrogens / adverse effects, pharmacology* Reproduction / drug effects*, physiology |
| Grant Support | |
ID/Acronym/Agency:
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R01-ES016001/ES/NIEHS NIH HHS; Z01-ES102405/ES/NIEHS NIH HHS; ZIA ES102405-04/ES/NIEHS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Phytoestrogens |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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