Document Detail


Reproductive outcomes among male and female workers at an aluminum smelter.
MedLine Citation:
PMID:  20134342     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Several adverse pregnancy outcomes were reported among female laboratory workers in a North American aluminum smelter. To determine whether these outcomes were associated with any occupational exposure at the plant, a cross-sectional survey was undertaken.
METHODS: Rates of miscarriage, premature singleton birth, and major congenital anomaly occurring during employment were compared with a reference group comprised of all pregnancies that occurred before employment.
RESULTS: Among female workers, the excess of congenital anomalies among female laboratory workers that defined the initial cluster was observed, but no specific pattern was found.
CONCLUSIONS: On the basis of these analyses, the increase in congenital anomalies could not be attributed to occupational exposures at the smelter nor could potential exposure likely explain the diverse anomalies described.
Authors:
Carine J Sakr; Oyebode A Taiwo; Deron H Galusha; Martin D Slade; Martha G Fiellin; Felicia Bayer; David A Savitz; Mark R Cullen
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine     Volume:  52     ISSN:  1536-5948     ISO Abbreviation:  J. Occup. Environ. Med.     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-10     Completed Date:  2010-04-23     Revised Date:  2011-08-01    
Medline Journal Info:
Nlm Unique ID:  9504688     Medline TA:  J Occup Environ Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  137-43     Citation Subset:  IM    
Affiliation:
Department of Occupational Medicine and Environmental Health, Yale University School of Medicine, New Haven, CT, USA. carine.sakr@yale.edu
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MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous / epidemiology
Adult
Aluminum / adverse effects*
Chi-Square Distribution
Congenital Abnormalities / epidemiology
Cross-Sectional Studies
Female
Humans
Laboratory Personnel / statistics & numerical data
Logistic Models
Male
Metallurgy* / manpower
Multivariate Analysis
Occupational Exposure / adverse effects*
Odds Ratio
Pregnancy
Pregnancy Outcome / epidemiology*
Premature Birth / epidemiology
Sex Factors
Time Factors
Grant Support
ID/Acronym/Agency:
1R01AG026291/AG/NIA NIH HHS; R01 AG026291-01A1/AG/NIA NIH HHS
Chemical
Reg. No./Substance:
7429-90-5/Aluminum
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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