Document Detail

Reproduction and ulcerative colitis: a review.
MedLine Citation:
PMID:  15971486     Owner:  NLM     Status:  MEDLINE    
Ulcerative colitis is a chronic inflammatory bowel disease. The onset peaks at age 15-30 years and coincides with the reproductive period. We screened and summarized the relevant English-language publications (Entrez-PubMed) on ulcerative colitis, fertility and pregnancy. The presence of ulcerative colitis per se does not seem to significantly alterfertility in young women. However, associated conditions, such as active disease, surgical interventions and medication, may interfere with reproduction. It is difficult to draw conclusions regarding the effect of ulcerative colitis on pregnancy outcome in terms of pregnancy loss, intrauterine growth restriction, low birth weight, preterm labor, stillbirth and perinatal mortality. Nevertheless, it appears that major complications do not occur in ulcerative colitis patients more frequently than in healthy women. The rate of exacerbation is probably the same for pregnant and nonpregnant women. Disease control during pregnancy is of the utmost importance. Fortunately, most drugs can by used safely during pregnancy.
Hen Y Sela; Nathan Rojansky; Alon Y Hershko
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  50     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-06-23     Completed Date:  2005-09-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  361-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center, Ein- Kerem, Jerusalem, Israel.
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MeSH Terms
Colitis, Ulcerative / complications*
Infertility / etiology*
Pregnancy Complications / etiology*
Pregnancy Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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