Document Detail

Reproduction in Down syndrome.
MedLine Citation:
PMID:  6211644     Owner:  NLM     Status:  MEDLINE    
A new case of pregnancy in a 29-year-old woman with trisomy 21 is described. She gave birth to a male infant, chromosomally and phenotypically normal, who died the day after delivery due to prematurity. Thirty pregnancies of 26 affected mothers, including the present woman, resulted in 10 children with Down syndrome, 18 children (1 set of twins) without Down syndrome, and 3 spontaneous abortions. Although rare, pregnancies in women with Down syndrome could become more frequent, increasing the importance of genetic, reproductive, and obstetric problems. These problems are reviewed with special reference to the occurrence of nonspecific abnormalities in chromosomally normal children, difficulties in labor and delivery, and frequency of prematurity and low birth weight.
L Bovicelli; L F Orsini; N Rizzo; V Montacuti; M Bacchetta
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  59     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1982 Jun 
Date Detail:
Created Date:  1982-08-14     Completed Date:  1982-08-14     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  13S-7S     Citation Subset:  AIM; IM    
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MeSH Terms
Down Syndrome / genetics*
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature
Pregnancy Complications*

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