| Reproducibility of volume and densitometric measures of emphysema on repeat computed tomography with an interval of 1 week. | |
| | |
MedLine Citation:
|
PMID: 22011903 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
OBJECTIVES: The reproducibilities of CT lung volume and densitometric measures of emphysema were assessed over 1 week. The influence of breathhold on reproducibility was assessed. METHODS: HRCT was performed on 44 subjects at inspiration on two visits with a 7-day interval. CT lung volume, relative area below -950HU (RA950-raw), and 15th percentile density (PD15-raw) were computed. Volume correction was used to obtain RA950-adj and PD15-adj. Reproducibilities between visits were assessed using concordance correlation coefficient (CCC) and repeatability coefficient (RC). Reproducibilities were compared between raw and adjusted measures. Differences between visits were computed for volume and density measures. Correlations were computed for density differences versus volume difference. Subgroup analysis was performed using a 0.25 L volume difference threshold. RESULTS: High CCC were observed for all measures in full group (CCC > 0.97). Reproducibilities of volume (RC = 0.67 L), RA950-raw (RC = 2.3%), and PD15-raw (RC = 10.6HU) were observed. Volume correction significantly improved PD15 (RC = 3.6HU) but not RA950 (RC = 1.7%). RA950-raw and PD15-raw had significantly better RC in <0.25 L subgroup than ≥0.25 L. Significant correlations with volume were observed for RA950-raw and PD15-raw (R (2) > 0.71), but not RA950-adj or PD15-adj (R (2) < 0.11). CONCLUSIONS: Good breathhold and RA950 reproducibilities were achieved. PD15 was less reproducible but improved with volume correction or superior breathhold reproduction. KEY POINTS : • Good breath-hold reproducibility is achievable between multiple CT examinations. • Reproducibility of densitometric measures may be improved by statistical volume correction. • Volume correction may result in decreased signal. • Densitometric reproducibility may also be improved by achieving good breath-hold reproduction. • Careful consideration of signal and noise is necessary in reproducibility assessment. |
| | |
Authors:
|
Daniel Chong; Matthew S Brown; Hyun J Kim; Eva M van Rikxoort; Laura Guzman; Michael F McNitt-Gray; Maryam Khatonabadi; Maya Galperin-Aizenberg; Heidi Coy; Katherine Yang; Yongha Jung; Jonathan G Goldin |
Related Documents
:
|
8115503 - Apert syndrome: quantitative assessment by ct scan of presenting deformity and surgical... 9162123 - Current status and new developments in techniques for imaging the nose and sinuses. 12608723 - The effect of changes in tooth position of unerupted canines on cephalograms. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-10-20 |
Journal Detail:
|
Title: European radiology Volume: - ISSN: 1432-1084 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-10-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Center for Computer Vision and Imaging Biomarkers, David Geffen School of Medicine, UCLA, 924 Westwood Blvd., Ste. 615, Los Angeles, CA, USA, dchong@mednet.ucla.edu. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Ligature of external carotid artery as an optional technique in a patient with von Willebrand diseas...
Next Document: Three-dimensional measurements of the lower extremity in children and adolescents using a low-dose b...