Document Detail

Reproducibility of tilt-table test result in patients with malignant neurocardiogenic syncope.
MedLine Citation:
PMID:  15317550     Owner:  NLM     Status:  MEDLINE    
The indication for permanent pacemaker remains controversial in malignant neurocardiogenic syncope. A highly reproducible prolonged pause during a repeat head-up tilt-table testing may identify a subgroup of neurally mediated syncope with a prominent and consistent cardioinhibitory component. Seven patients (3 females) with a mean age of 30 years (23-44 years) were diagnosed to have malignant neurocardiogenic -syncope; all are classified according to the Vasovagal Syncope International Study as 2B type, with observed sinus pauses ranged from 3 s to 26 s of which only 1 demonstrated a reproducible sinus pause. No recurrence of syncope was clinically observed in patients during the follow-up period. Of 6 patients treated non--pharmacologically, one required a beta-blocker and none required a permanent pacemaker. Prolonged asystole manifest during head-up tilt-table testing is a poorly reproducible phenomenon and permanent pacemaker implantation in malignant neurocardiogenic syncope should not be a first line therapy.
A R Omar; K-S Ng; W-L Ng; A Sutandar
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Internal medicine journal     Volume:  34     ISSN:  1444-0903     ISO Abbreviation:  Intern Med J     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-08-19     Completed Date:  2004-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092952     Medline TA:  Intern Med J     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  504-6     Citation Subset:  IM    
Cardiac Department, National University Hospital, Singapore.
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MeSH Terms
Cardiovascular Agents / therapeutic use
Pacemaker, Artificial / utilization
Reproducibility of Results
Syncope, Vasovagal / diagnosis*,  drug therapy
Tilt-Table Test*
Reg. No./Substance:
0/Cardiovascular Agents

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